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Substance P participates in immune-mediated hepatic injury induced by concanavalin A in mice and stimulates cytokine synthesis in Kupffer cells

Studies have indicated that the immune system plays a pivotal role in hepatitis. Substance P (SP) has been shown to modulate the immune response. In order to investigate the role of SP in liver injury and to determine whether it leads to pro-inflammatory signaling, we established a mouse model of he...

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Detalles Bibliográficos
Autores principales: YANG, YAN, YAN, MING, ZHANG, HAITAO, WANG, XUPING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786810/
https://www.ncbi.nlm.nih.gov/pubmed/24137208
http://dx.doi.org/10.3892/etm.2013.1152