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Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective

AIMS: We sought to develop descriptions of health states associated with daytime and nocturnal hypoglycemia in a structured fashion from the patient’s perspective under different combinations of severity and frequency of hypoglycemic events. METHODS: An expert meeting followed by two patient focus g...

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Autores principales: Harris, Stewart B, Khunti, Kamlesh, Landin-Olsson, Mona, Galbo-Jørgensen, Claus B, Bøgelund, Mette, Chubb, Barrie, Gundgaard, Jens, Evans, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786816/
https://www.ncbi.nlm.nih.gov/pubmed/24086103
http://dx.doi.org/10.2147/PPA.S46805
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author Harris, Stewart B
Khunti, Kamlesh
Landin-Olsson, Mona
Galbo-Jørgensen, Claus B
Bøgelund, Mette
Chubb, Barrie
Gundgaard, Jens
Evans, Marc
author_facet Harris, Stewart B
Khunti, Kamlesh
Landin-Olsson, Mona
Galbo-Jørgensen, Claus B
Bøgelund, Mette
Chubb, Barrie
Gundgaard, Jens
Evans, Marc
author_sort Harris, Stewart B
collection PubMed
description AIMS: We sought to develop descriptions of health states associated with daytime and nocturnal hypoglycemia in a structured fashion from the patient’s perspective under different combinations of severity and frequency of hypoglycemic events. METHODS: An expert meeting followed by two patient focus groups was used to develop comprehensive descriptions of acute consequences of severe and non-severe, daytime and nocturnal hypoglycemia. Patients with diabetes (type 1 = 85, type 2 = 162) from a survey panel then validated these descriptions and assessed how often they worried and took different actions to prevent hypoglycemia. Severity and frequency of hypoglycemia were compared with respect to how often people worried and took actions to prevent an event. The effect of hypoglycemia on 35 different life activities was quantitatively compared for patients who had and had not experienced a severe hypoglycemic event. RESULTS: At least 95% of respondents agreed that the detailed patient-level descriptions of health states accurately reflected their experience of severe and non-severe, daytime and nocturnal hypoglycemia, thereby validating these descriptions. Respondents who had experienced a severe hypoglycemic event were generally more adversely affected in their worries and actions and life events than those who experienced only non-severe events; those who experienced nocturnal events were more affected than those who experienced only daytime events. CONCLUSION: The negative psychosocial consequences and undesirable compensatory behaviors arising from hypoglycemia underscore the importance of preventing severe episodes, particularly severe nocturnal episodes. These validated descriptions for hypoglycemia from the patient’s perspective may also help inform future qualitative and quantitative research.
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spelling pubmed-37868162013-10-01 Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective Harris, Stewart B Khunti, Kamlesh Landin-Olsson, Mona Galbo-Jørgensen, Claus B Bøgelund, Mette Chubb, Barrie Gundgaard, Jens Evans, Marc Patient Prefer Adherence Original Research AIMS: We sought to develop descriptions of health states associated with daytime and nocturnal hypoglycemia in a structured fashion from the patient’s perspective under different combinations of severity and frequency of hypoglycemic events. METHODS: An expert meeting followed by two patient focus groups was used to develop comprehensive descriptions of acute consequences of severe and non-severe, daytime and nocturnal hypoglycemia. Patients with diabetes (type 1 = 85, type 2 = 162) from a survey panel then validated these descriptions and assessed how often they worried and took different actions to prevent hypoglycemia. Severity and frequency of hypoglycemia were compared with respect to how often people worried and took actions to prevent an event. The effect of hypoglycemia on 35 different life activities was quantitatively compared for patients who had and had not experienced a severe hypoglycemic event. RESULTS: At least 95% of respondents agreed that the detailed patient-level descriptions of health states accurately reflected their experience of severe and non-severe, daytime and nocturnal hypoglycemia, thereby validating these descriptions. Respondents who had experienced a severe hypoglycemic event were generally more adversely affected in their worries and actions and life events than those who experienced only non-severe events; those who experienced nocturnal events were more affected than those who experienced only daytime events. CONCLUSION: The negative psychosocial consequences and undesirable compensatory behaviors arising from hypoglycemia underscore the importance of preventing severe episodes, particularly severe nocturnal episodes. These validated descriptions for hypoglycemia from the patient’s perspective may also help inform future qualitative and quantitative research. Dove Medical Press 2013-09-16 /pmc/articles/PMC3786816/ /pubmed/24086103 http://dx.doi.org/10.2147/PPA.S46805 Text en © 2013 Harris et al, publisher and licensee Dove Medical Press Ltd This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.
spellingShingle Original Research
Harris, Stewart B
Khunti, Kamlesh
Landin-Olsson, Mona
Galbo-Jørgensen, Claus B
Bøgelund, Mette
Chubb, Barrie
Gundgaard, Jens
Evans, Marc
Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title_full Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title_fullStr Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title_full_unstemmed Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title_short Descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
title_sort descriptions of health states associated with increasing severity and frequency of hypoglycemia: a patient-level perspective
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786816/
https://www.ncbi.nlm.nih.gov/pubmed/24086103
http://dx.doi.org/10.2147/PPA.S46805
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