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Edaravone Protected Human Brain Microvascular Endothelial Cells from Methylglyoxal-Induced Injury by Inhibiting AGEs/RAGE/Oxidative Stress

Subjects with diabetes experience an increased risk of cerebrovascular disease and stroke compared with nondiabetic age-matched individuals. Increased formation of reactive physiological dicarbonyl compound methylglyoxal (MGO) seems to be implicated in the development of diabetic vascular complicati...

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Detalles Bibliográficos
Autores principales: Li, Wenlu, Xu, Hongjiao, Hu, Yangmin, He, Ping, Ni, Zhenzhen, Xu, Huimin, Zhang, Zhongmiao, Dai, Haibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786889/
https://www.ncbi.nlm.nih.gov/pubmed/24098758
http://dx.doi.org/10.1371/journal.pone.0076025