Fatty Liver Is Associated with Transcriptional Downregulation of Stearoyl-CoA Desaturase and Impaired Protein Dimerization

AIMS AND METHODS: We evaluated the modulation of liver stearoyl-CoA desaturase-1 (Scd1) by dietary factors and insulin resistance (IR) in two experimental models of high-fat diet (HFD)-induced nonalcoholic fatty liver disease (NAFLD). The first model included Sprague Dawley (SD) rats that developed...

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Detalles Bibliográficos
Autores principales: Fernández Gianotti, Tomas, Burgueño, Adriana, Gonzales Mansilla, Noelia, Pirola, Carlos Jose, Sookoian, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786952/
https://www.ncbi.nlm.nih.gov/pubmed/24098813
http://dx.doi.org/10.1371/journal.pone.0076912

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