MIP-2A Is a Novel Target of an Anilinoquinazoline Derivative for Inhibition of Tumour Cell Proliferation

We recently identified a novel anilinoquinazoline derivative, Q15, as a potent apoptosis inducer in a panel of human cancer cell lines and determined that Q15 targets hCAP-G2, a subunit of condensin II complex, leading to abnormal cell division. However, whether the defect in normal cell division di...

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Detalles Bibliográficos
Autores principales: Tokunaga, Mayuko, Shiheido, Hirokazu, Tabata, Noriko, Sakuma-Yonemura, Yuko, Takashima, Hideaki, Horisawa, Kenichi, Doi, Nobuhide, Yanagawa, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786957/
https://www.ncbi.nlm.nih.gov/pubmed/24098805
http://dx.doi.org/10.1371/journal.pone.0076774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786957/
https://www.ncbi.nlm.nih.gov/pubmed/24098805
http://dx.doi.org/10.1371/journal.pone.0076774

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