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Mechanisms Involved in the Beneficial Effects of Spironolactone after Myocardial Infarction

INTRODUCTION: Our objective was to analyze the effect of spironolactone on cardiac remodeling after experimental myocardial infarction (MI), assessed by matricellular proteins levels, cardiac collagen amount and distribution, myocardial tissue metalloproteinase inhibitor-1(TIMP-1) concentration, myo...

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Detalles Bibliográficos
Autores principales: Minicucci, Marcos F., dos Santos, Priscila P., Rafacho, Bruna P. M., Gonçalves, Andrea F., Silva, Renata A. C., Chiuso-Minicucci, Fernanda, Azevedo, Paula S., Polegato, Bertha F., Okoshi, Katashi, Pereira, Elenize J., Paiva, Sergio A. R., Zornoff, Leonardo A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786966/
https://www.ncbi.nlm.nih.gov/pubmed/24098808
http://dx.doi.org/10.1371/journal.pone.0076866