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The Ether Lipid Precursor Hexadecylglycerol Causes Major Changes in the Lipidome of HEp-2 Cells

The ether-lipid precursor sn-1-O-hexadecylglycerol (HG) can be used to compensate for early metabolic defects in ether-lipid biosynthesis. To investigate a possible metabolic link between ether-linked phospholipids and the rest of the cellular lipidome, we incubated HEp-2 cells with HG. Mass spectro...

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Detalles Bibliográficos
Autores principales: Bergan, Jonas, Skotland, Tore, Sylvänne, Tuulia, Simolin, Helena, Ekroos, Kim, Sandvig, Kirsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3786967/
https://www.ncbi.nlm.nih.gov/pubmed/24098742
http://dx.doi.org/10.1371/journal.pone.0075904