Cargando…

Radiation therapy induces the DNA damage response in peripheral blood

Stereotactic body radiation therapy (SBRT) is a radiotherapy modality that delivers highly conformal, ablative doses to a well-defined target. Here, using a semiquantitative multiplexed assay to analyze ATM and H2AX phosphorylation, we show that ATM kinase activity in peripheral blood mononuclear ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bakkenist, Christopher J., Czambel, R. Kenneth, Clump, David A., Greenberger, Joel S., Beumer, Jan H., Schmitz, John C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787146/ https://www.ncbi.nlm.nih.gov/pubmed/23900392

Ejemplares similares

A quasi-quantitative dual multiplexed immunoblot method to simultaneously analyze ATM and H2AX Phosphorylation in human peripheral blood mononuclear cells
por: Bakkenist, Christopher J., et al.
Publicado: (2015)

ATR kinase activation in G1 phase facilitates the repair of ionizing radiation-induced DNA damage
por: Gamper, Armin M., et al.
Publicado: (2013)

Dose-Dependent Bioavailability and Tissue Distribution of the ATR Inhibitor AZD6738 (ceralasertib) in Mice
por: Kiesel, Brian F., et al.
Publicado: (2022)

Strategies for Discovery of Small Molecule Radiation Protectors and Radiation Mitigators
por: Greenberger, Joel S., et al.
Publicado: (2012)

DNA damage response pathways in cancer causation and treatment
por: Kastan, MB, et al.
Publicado: (2005)

The schedule of ATR inhibitor AZD6738 can potentiate or abolish antitumor immune responses to radiotherapy
por: Vendetti, Frank P., et al.
Publicado: (2023)

The Telomeric Protein TRF2 Binds the ATM Kinase and Can Inhibit the ATM-Dependent DNA Damage Response
por: Karlseder, Jan, et al.
Publicado: (2004)

Differential DNA Damage Response of Peripheral Blood Lymphocyte Populations
por: Felgentreff, Kerstin, et al.
Publicado: (2021)

Pharmacologic ATM but not ATR kinase inhibition abrogates p21-dependent G1 arrest and promotes gastrointestinal syndrome after total body irradiation
por: Vendetti, Frank P., et al.
Publicado: (2017)

Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma: ATM, ATR and FA in lung carcinoma
por: Beumer, Jan H., et al.
Publicado: (2015)

DNA damage in peripheral blood leukocytes in tobacco users
por: Guttikonda, Venkateswara Rao, et al.
Publicado: (2014)

Altered Gene Expression and DNA Damage in Peripheral Blood Cells from Friedreich's Ataxia Patients: Cellular Model of Pathology
por: Haugen, Astrid C., et al.
Publicado: (2010)

The DNA damage response in immunotherapy and radiation
por: Samstein, Robert M., et al.
Publicado: (2018)

Interplay of space radiation and microgravity in DNA damage and DNA damage response
por: Moreno-Villanueva, María, et al.
Publicado: (2017)

Simultaneous induction of dispersed and clustered DNA lesions compromises DNA damage response in human peripheral blood lymphocytes
por: Cheng, Lei, et al.
Publicado: (2018)

Radiopotentiation Profiling of Multiple Inhibitors of the DNA Damage Response for Early Clinical Development
por: Gill, Sonja J., et al.
Publicado: (2021)

Cisplatin-DNA damage and repair in peripheral blood leukocytes in vivo and in vitro.
por: Dabholkar, M, et al.
Publicado: (1992)

Monitoring DNA Damage and Repair in Peripheral Blood Mononuclear Cells of Lung Cancer Radiotherapy Patients
por: Lobachevsky, Pavel N., et al.
Publicado: (2020)

Peripheral Blood Mitochondrial DNA Damage as a Potential Noninvasive Biomarker of Diabetic Retinopathy
por: Mishra, Manish, et al.
Publicado: (2016)

Chromatin modifications and the DNA damage response to ionizing radiation
por: Kumar, Rakesh, et al.
Publicado: (2013)

Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation, and polypharmacological strategies
por: Liu, Bing, et al.
Publicado: (2014)

Oxidative DNA Damage to Sperm Cells and Peripheral Blood Leukocytes in Infertile Men
por: Taken, Kerem, et al.
Publicado: (2016)

Stereotactic Ablative Radiation Therapy for Unresectable Colorectal Oligometastases
por: Sutera, Philip, et al.
Publicado: (2018)

Integrated Molecular Analysis Indicates Undetectable Change in DNA Damage in Mice after Continuous Irradiation at ~ 400-fold Natural Background Radiation
por: Olipitz, Werner, et al.
Publicado: (2012)

Repair of radiation damage to DNA
por: Willers, H, et al.
Publicado: (2004)

Long-Term Patient-Reported Quality of Life After Stereotactic Body Radiation Therapy for Recurrent, Previously-Irradiated Head and Neck Cancer
por: Thomas, Joel, et al.
Publicado: (2020)

DNA Damage Responses following Exposure to Modulated Radiation Fields
por: Trainor, Colman, et al.
Publicado: (2012)

The Cellular Response to Complex DNA Damage Induced by Ionising Radiation
por: Wilkinson, Beth, et al.
Publicado: (2023)

Chromatin and the Cellular Response to Particle Radiation-Induced Oxidative and Clustered DNA Damage
por: Danforth, John M., et al.
Publicado: (2022)

Allogeneic adipose‐derived stem cells mitigate acute radiation syndrome by the rescue of damaged bone marrow cells from apoptosis
por: Chinnapaka, Somaiah, et al.
Publicado: (2021)

Serum 8-Hydroxy-2′-Deoxyguanosine Level as a Potential Biomarker of Oxidative DNA Damage Induced by Ionizing Radiation in Human Peripheral Blood
por: Gao, Yu, et al.
Publicado: (2019)

Radiation Dose-Rate and DNA Damage
por: Melzer, Peter
Publicado: (2012)

UVA Radiation, DNA Damage, and Melanoma
por: Jin, Seung-Gi, et al.
Publicado: (2022)

Stereotactic Body Radiation Therapy for Pulmonary Oligometastases Arising from Non-lung Primaries in Patients Without Extrapulmonary Disease
por: Dohopolski, Michael J, et al.
Publicado: (2018)

Stereotactic Ablative Radiosurgery for Locally Advanced or Recurrent Skull Base Malignancies with Prior External Beam Radiation Therapy
por: Xu, Karen M., et al.
Publicado: (2015)

DNA damage response and preleukemic fusion genes induced by ionizing radiation in umbilical cord blood hematopoietic stem cells
por: Kosik, Pavol, et al.
Publicado: (2020)

Targeting DNA damage response in cancer therapy
por: Hosoya, Noriko, et al.
Publicado: (2014)

Targeting the DNA damage response for cancer therapy
por: Curtin, Nicola J.
Publicado: (2023)

Targeting the DNA Damage Response for Cancer Therapy
por: Wang, Ruoxi, et al.
Publicado: (2023)

DNA damage in peripheral blood mononuclear cells and neutrophils of dairy cows during the transition period
por: Tharwat, M., et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_s23e61nvful3v7pp8i8tc7l626