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Structure Activity Relationships in Alkylammonium C(12)-Gemini Surfactants Used as Dermal Permeation Enhancers
The purpose of this study was to determine the ability and the safety of a series of alkylammonium C12-gemini surfactants to act as permeation enhancers for three model drugs, namely lidocaine HCl, caffeine, and ketoprofen. In vitro permeation studies across dermatomed porcine skin were performed ov...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787226/ https://www.ncbi.nlm.nih.gov/pubmed/23959685 http://dx.doi.org/10.1208/s12248-013-9518-y |