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Thermodynamics of Peptide-MHC Class II Interactions: Not all Complexes are Created Equal
The adaptive immune response begins when CD4+ T cells recognize antigenic peptides bound to class II molecules of the Major Histocompatibility Complex (MHCII). The interaction between peptides and MHCII has been historically interpreted as a rigid docking event. However, this model has been challeng...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787305/ https://www.ncbi.nlm.nih.gov/pubmed/24101920 http://dx.doi.org/10.3389/fimmu.2013.00308 |