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Locally Applied Valproate Enhances Survival in Rats after Neocortical Treatment with Tetanus Toxin and Cobalt Chloride

Purpose. In neocortical epilepsies not satisfactorily responsive to systemic antiepileptic drug therapy, local application of antiepileptic agents onto the epileptic focus may enhance treatment efficacy and tolerability. We describe the effects of focally applied valproate (VPA) in a newly emerging...

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Detalles Bibliográficos
Autores principales: Altenmüller, Dirk-Matthias, Hebel, Jonas M., Rassner, Michael P., Volz, Silvanie, Freiman, Thomas M., Feuerstein, Thomas J., Zentner, Josef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787549/
https://www.ncbi.nlm.nih.gov/pubmed/24151604
http://dx.doi.org/10.1155/2013/497485