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Locally Applied Valproate Enhances Survival in Rats after Neocortical Treatment with Tetanus Toxin and Cobalt Chloride
Purpose. In neocortical epilepsies not satisfactorily responsive to systemic antiepileptic drug therapy, local application of antiepileptic agents onto the epileptic focus may enhance treatment efficacy and tolerability. We describe the effects of focally applied valproate (VPA) in a newly emerging...
Autores principales: | Altenmüller, Dirk-Matthias, Hebel, Jonas M., Rassner, Michael P., Volz, Silvanie, Freiman, Thomas M., Feuerstein, Thomas J., Zentner, Josef |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787549/ https://www.ncbi.nlm.nih.gov/pubmed/24151604 http://dx.doi.org/10.1155/2013/497485 |
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