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Proteolytic Processing of Von Willebrand Factor by Adamts13 and Leukocyte Proteases

ADAMTS13 is a 190 kDa zinc protease encoded by a gene located on chromosome 9q34. This protease specifically hydrolyzes von Willebrand factor (VWF) multimers, thus causing VWF size reduction. ADAMTS13 belongs to the A Disintegrin And Metalloprotease with ThromboSpondin type 1 repeats (ADAMTS) family...

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Detalles Bibliográficos
Autores principales:	Lancellotti, Stefano, Basso, Maria, De Cristofaro, Raimondo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Università Cattolica del Sacro Cuore 2013
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787661/ https://www.ncbi.nlm.nih.gov/pubmed/24106608 http://dx.doi.org/10.4084/MJHID.2013.058

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