Evidence for Deep Phylogenetic Conservation of Exonic Splice-Related Constraints: Splice-Related Skews at Exonic Ends in the Brown Alga Ectocarpus Are Common and Resemble Those Seen in Humans

The control of RNA splicing is often modulated by exonic motifs near splice sites. Chief among these are exonic splice enhancers (ESEs). Well-described ESEs in mammals are purine rich and cause predictable skews in codon and amino acid usage toward exonic ends. Looking across species, those with rel...

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Detalles Bibliográficos
Autores principales: Wu, XianMing, Tronholm, Ana, Cáceres, Eva Fernández, Tovar-Corona, Jaime M., Chen, Lu, Urrutia, Araxi O., Hurst, Laurence D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787667/
https://www.ncbi.nlm.nih.gov/pubmed/23902749
http://dx.doi.org/10.1093/gbe/evt115

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