Cargando…
GCY-8, PDE-2, and NCS-1 are critical elements of the cGMP-dependent thermotransduction cascade in the AFD neurons responsible for C. elegans thermotaxis
Certain thermoreceptor neurons are sensitive to tiny thermal fluctuations (0.01°C or less) and maintain their sensitivity across a wide range of ambient temperatures through a process of adaptation, but understanding of the biochemical basis for this performance is rudimentary. Prior studies of the...
Autores principales: | Wang, Dong, O’Halloran, Damien, Goodman, Miriam B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787776/ https://www.ncbi.nlm.nih.gov/pubmed/24081984 http://dx.doi.org/10.1085/jgp.201310959 |
Ejemplares similares
-
The role of the AFD neuron in C. elegans thermotaxis analyzed using femtosecond laser ablation
por: Chung, Samuel H, et al.
Publicado: (2006) -
PDE5 says NO to cGMP
por: LeBrasseur, Nicole
Publicado: (2003) -
cGMP dynamics that underlies thermosensation in temperature-sensing neuron regulates thermotaxis behavior in C. elegans
por: Aok, Ichiro, et al.
Publicado: (2022) -
Identification of the AFD neuron as the site of action of the CREB protein in Caenorhabditis elegans thermotaxis
por: Nishida, Yukuo, et al.
Publicado: (2011) -
Direct activation of PDE5 by cGMP: long-term effects within NO/cGMP signaling
por: Mullershausen, Florian, et al.
Publicado: (2003)