CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells

Mutations in the CDKL5 (cyclin-dependent kinase-like 5) gene are associated with a severe epileptic encephalopathy (early infantile epileptic encephalopathy type 2, EIEE2) characterized by early-onset intractable seizures, infantile spasms, severe developmental delay, intellectual disability, and Re...

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Detalles Bibliográficos
Autores principales: Valli, Emanuele, Trazzi, Stefania, Fuchs, Claudia, Erriquez, Daniela, Bartesaghi, Renata, Perini, Giovanni, Ciani, Elisabetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Pub. Co 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787793/
https://www.ncbi.nlm.nih.gov/pubmed/22921766
http://dx.doi.org/10.1016/j.bbagrm.2012.08.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787793/
https://www.ncbi.nlm.nih.gov/pubmed/22921766
http://dx.doi.org/10.1016/j.bbagrm.2012.08.001

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