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CDKL5, a novel MYCN-repressed gene, blocks cell cycle and promotes differentiation of neuronal cells
Mutations in the CDKL5 (cyclin-dependent kinase-like 5) gene are associated with a severe epileptic encephalopathy (early infantile epileptic encephalopathy type 2, EIEE2) characterized by early-onset intractable seizures, infantile spasms, severe developmental delay, intellectual disability, and Re...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier Pub. Co
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787793/ https://www.ncbi.nlm.nih.gov/pubmed/22921766 http://dx.doi.org/10.1016/j.bbagrm.2012.08.001 |