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‘Decoy’ and ‘non-decoy’ functions of DcR3 promote malignant potential in human malignant fibrous histiocytoma cells

Decoy receptor 3 (DcR3) is a soluble secreted protein that belongs to the tumor necrosis factor receptor (TNFR) superfamily. DcR3 inhibits the Fas ligand (FasL)/Fas apoptotic pathway by binding to FasL, competitively with Fas receptor. Previous studies have reported that overexpression of DcR3 has b...

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Detalles Bibliográficos
Autores principales: TODA, MITSUNORI, KAWAMOTO, TERUYA, UEHA, TAKESHI, KISHIMOTO, KENTA, HARA, HITOMI, FUKASE, NAOMASA, ONISHI, YASUO, HARADA, RISA, MINODA, MASAYA, KUROSAKA, MASAHIRO, AKISUE, TOSHIHIRO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3787885/
https://www.ncbi.nlm.nih.gov/pubmed/23817777
http://dx.doi.org/10.3892/ijo.2013.1999

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