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Increased Oxidative Metabolism and Neurotransmitter Cycling in the Brain of Mice Lacking the Thyroid Hormone Transporter Slc16a2 (Mct8)
Mutations of the monocarboxylate transporter 8 (MCT8) cause a severe X-linked intellectual deficit and neurological impairment. MCT8 is a specific thyroid hormone (T(4) and T(3)) transporter and the patients also present unusual abnormalities in the serum profile of thyroid hormone concentrations du...
Autores principales: | Rodrigues, Tiago B., Ceballos, Ainhoa, Grijota-Martínez, Carmen, Nuñez, Barbara, Refetoff, Samuel, Cerdán, Sebastian, Morte, Beatriz, Bernal, Juan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788064/ https://www.ncbi.nlm.nih.gov/pubmed/24098341 http://dx.doi.org/10.1371/journal.pone.0074621 |
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