Selection of a Novel Anti-Nicotine Vaccine: Influence of Antigen Design on Antibody Function in Mice

Anti-nicotine vaccines may aid smoking cessation via the induction of anti-nicotine antibodies (Ab) which reduce nicotine entering the brain, and hence the associated reward. Ab function depends on both the quantity (titer) and the quality (affinity) of the Ab. Anti-nicotine vaccines tested previous...

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Detalles Bibliográficos
Autores principales: Pryde, David C., Jones, Lyn H., Gervais, David P., Stead, David R., Blakemore, David C., Selby, Matthew D., Brown, Alan D., Coe, Jotham W., Badland, Matthew, Beal, David M., Glen, Rebecca, Wharton, Yvonne, Miller, Gavin J., White, Phil, Zhang, Ningli, Benoit, Michelle, Robertson, Karen, Merson, James R., Davis, Heather L., McCluskie, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788104/
https://www.ncbi.nlm.nih.gov/pubmed/24098532
http://dx.doi.org/10.1371/journal.pone.0076557

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