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Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins

S100 proteins are small dimeric calcium-binding proteins which control cell cycle, growth and differentiation via interactions with different target proteins. Intrinsic disorder is a hallmark among many signaling proteins and S100 proteins have been proposed to contain disorder-prone regions. Intere...

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Detalles Bibliográficos
Autores principales: Carvalho, Sofia B., Botelho, Hugo M., Leal, Sónia S., Cardoso, Isabel, Fritz, Günter, Gomes, Cláudio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788126/
https://www.ncbi.nlm.nih.gov/pubmed/24098542
http://dx.doi.org/10.1371/journal.pone.0076629

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