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Intrinsically Disordered and Aggregation Prone Regions Underlie β-Aggregation in S100 Proteins
S100 proteins are small dimeric calcium-binding proteins which control cell cycle, growth and differentiation via interactions with different target proteins. Intrinsic disorder is a hallmark among many signaling proteins and S100 proteins have been proposed to contain disorder-prone regions. Intere...
Autores principales: | Carvalho, Sofia B., Botelho, Hugo M., Leal, Sónia S., Cardoso, Isabel, Fritz, Günter, Gomes, Cláudio M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788126/ https://www.ncbi.nlm.nih.gov/pubmed/24098542 http://dx.doi.org/10.1371/journal.pone.0076629 |
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