A Polymorphic 3’UTR Element in ATP1B1 Regulates Alternative Polyadenylation and Is Associated with Blood Pressure

Although variants in many genes have previously been shown to be associated with blood pressure (BP) levels, the molecular mechanism underlying these associations are mostly unknown. We identified a multi-allelic T-rich sequence (TRS) in the 3’UTR of ATP1B1 that varies in length and sequence composi...

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Detalles Bibliográficos
Autores principales: Prasad, Megana K., Bhalla, Kavita, Pan, Zhen Hua, O’Connell, Jeffrey R., Weder, Alan B., Chakravarti, Aravinda, Tian, Bin, Chang, Yen-Pei C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788127/
https://www.ncbi.nlm.nih.gov/pubmed/24098465
http://dx.doi.org/10.1371/journal.pone.0076290

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