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Netazepide, a Gastrin Receptor Antagonist, Normalises Tumour Biomarkers and Causes Regression of Type 1 Gastric Neuroendocrine Tumours in a Nonrandomised Trial of Patients with Chronic Atrophic Gastritis

INTRODUCTION: Autoimmune chronic atrophic gastritis (CAG) causes hypochlorhydria and hypergastrinaemia, which can lead to enterochromaffin-like (ECL) cell hyperplasia and gastric neuroendocrine tumours (type 1 gastric NETs). Most behave indolently, but some larger tumours metastasise. Antrectomy, wh...

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Detalles Bibliográficos
Autores principales: Moore, Andrew R., Boyce, Malcolm, Steele, Islay A., Campbell, Fiona, Varro, Andrea, Pritchard, D. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788129/
https://www.ncbi.nlm.nih.gov/pubmed/24098507
http://dx.doi.org/10.1371/journal.pone.0076462