Cargando…

The very many faces of presenilins and the γ-secretase complex

Presenilin is a central, catalytic component of the γ-secretase complex which conducts intramembrane cleavage of various protein substrates. Although identified and mainly studied through its role in the development of amyloid plaques in Alzheimer disease, γ-secretase has many other important functi...

Descripción completa

Detalles Bibliográficos
Autores principales: Smolarkiewicz, Michalina, Skrzypczak, Tomasz, Wojtaszek, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788181/
https://www.ncbi.nlm.nih.gov/pubmed/23504135
http://dx.doi.org/10.1007/s00709-013-0494-y

Ejemplares similares