Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A

We report a rare case of neurodegeneration with brain iron accumulation (NBIA) presented with episodic inspiratory stridor. A 10-year-old boy presented with 3-year history of gradually progressive spastic gait and generalized dystonia (involving all four limbs, neck, jaw, and speech). MRI brain show...

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Autores principales: Rai, Vinod, Goyal, Vinay, Shukla, Garima, Rath, Girija, Behari, Madhuri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788295/
https://www.ncbi.nlm.nih.gov/pubmed/24101831
http://dx.doi.org/10.4103/0972-2327.116919
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author Rai, Vinod
Goyal, Vinay
Shukla, Garima
Rath, Girija
Behari, Madhuri
author_facet Rai, Vinod
Goyal, Vinay
Shukla, Garima
Rath, Girija
Behari, Madhuri
author_sort Rai, Vinod
collection PubMed
description We report a rare case of neurodegeneration with brain iron accumulation (NBIA) presented with episodic inspiratory stridor. A 10-year-old boy presented with 3-year history of gradually progressive spastic gait and generalized dystonia (involving all four limbs, neck, jaw, and speech). MRI brain showed “Eye of Tiger” sign. He recently developed severe inspiratory stridor associated with almost gasping respiration. Direct video laryngoscopy showed paradoxical vocal cord closure during inspiration. He was treated with EMG-guided botulinum toxin-A injection given into bilateral thyroarytenoid muscles, resulting in dramatic response with complete disappearance of the stridor within a week. The effect lasted 18 months.
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spelling pubmed-37882952013-10-07 Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A Rai, Vinod Goyal, Vinay Shukla, Garima Rath, Girija Behari, Madhuri Ann Indian Acad Neurol Case Report We report a rare case of neurodegeneration with brain iron accumulation (NBIA) presented with episodic inspiratory stridor. A 10-year-old boy presented with 3-year history of gradually progressive spastic gait and generalized dystonia (involving all four limbs, neck, jaw, and speech). MRI brain showed “Eye of Tiger” sign. He recently developed severe inspiratory stridor associated with almost gasping respiration. Direct video laryngoscopy showed paradoxical vocal cord closure during inspiration. He was treated with EMG-guided botulinum toxin-A injection given into bilateral thyroarytenoid muscles, resulting in dramatic response with complete disappearance of the stridor within a week. The effect lasted 18 months. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3788295/ /pubmed/24101831 http://dx.doi.org/10.4103/0972-2327.116919 Text en Copyright: © Annals of Indian Academy of Neurology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Rai, Vinod
Goyal, Vinay
Shukla, Garima
Rath, Girija
Behari, Madhuri
Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title_full Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title_fullStr Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title_full_unstemmed Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title_short Adductor laryngeal breathing dystonia in NBIA treated with botulinum toxin-A
title_sort adductor laryngeal breathing dystonia in nbia treated with botulinum toxin-a
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788295/
https://www.ncbi.nlm.nih.gov/pubmed/24101831
http://dx.doi.org/10.4103/0972-2327.116919
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