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Insights on the functional interactions between miRNAs and copy number variations in the aging brain

MicroRNAs (miRNAs) are regulatory genetic elements that coordinate the expression of thousands of genes and play important roles in brain aging and neurodegeneration. DNA polymorphisms affecting miRNA biogenesis, dosage, and gene targeting may represent potentially functional variants. The consequen...

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Detalles Bibliográficos
Autores principales:	Persengiev, Stephan, Kondova, Ivanela, Bontrop, Ronald
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788589/ https://www.ncbi.nlm.nih.gov/pubmed/24106459 http://dx.doi.org/10.3389/fnmol.2013.00032

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