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Laminin and Type IV Collagen Isoform Substitutions Occur in Temporally and Spatially Distinct Patterns in Developing Kidney Glomerular Basement Membranes

Kidney glomerular basement membranes (GBMs) undergo laminin and type IV collagen isoform substitutions during glomerular development, which are believed to be required for maturation of the filtration barrier. Specifically, GBMs of earliest glomeruli contain laminin α1β1γ1 and collagen α1α2α1(IV), w...

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Detalles Bibliográficos
Autores principales: Abrahamson, Dale R., St. John, Patricia L., Stroganova, Larysa, Zelenchuk, Adrian, Steenhard, Brooke M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788627/
https://www.ncbi.nlm.nih.gov/pubmed/23896970
http://dx.doi.org/10.1369/0022155413501677