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Notch2-dependent classical dendritic cells orchestrate intestinal immunity against attaching and effacing bacterial pathogens
Defense against attaching and effacing (A/E) bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce protective mucosal responses. While CD4(+) and NKp46(+) innate lymphoid cells (ILCs) are the critical source of IL-22 during infection, the precise source of IL-23 i...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788683/ https://www.ncbi.nlm.nih.gov/pubmed/23913046 http://dx.doi.org/10.1038/ni.2679 |