Notch2-dependent classical dendritic cells orchestrate intestinal immunity against attaching and effacing bacterial pathogens

Defense against attaching and effacing (A/E) bacteria requires the sequential generation of interleukin 23 (IL-23) and IL-22 to induce protective mucosal responses. While CD4(+) and NKp46(+) innate lymphoid cells (ILCs) are the critical source of IL-22 during infection, the precise source of IL-23 i...

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Detalles Bibliográficos
Autores principales: Satpathy, Ansuman T., Briseño, Carlos G., Lee, Jacob S., Ng, Dennis, Manieri, Nicholas A., KC, Wumesh, Wu, Xiaodi, Thomas, Stephanie R., Lee, Wan-Ling, Turkoz, Mustafa, McDonald, Keely G., Meredith, Matthew M., Song, Christina, Guidos, Cynthia J., Newberry, Rodney D., Ouyang, Wenjun, Murphy, Theresa L., Stappenbeck, Thaddeus S., Gommerman, Jennifer L., Nussenzweig, Michel C., Colonna, Marco, Kopan, Raphael, Murphy, Kenneth M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788683/
https://www.ncbi.nlm.nih.gov/pubmed/23913046
http://dx.doi.org/10.1038/ni.2679

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