PD-0332991, a CDK4/6 Inhibitor, Significantly Prolongs Survival in a Genetically Engineered Mouse Model of Brainstem Glioma

Diffuse intrinsic pontine glioma (DIPG) is an incurable tumor that arises in the brainstem of children. To date there is not a single approved drug to effectively treat these tumors and thus novel therapies are desperately needed. Recent studies suggest that a significant fraction of these tumors co...

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Detalles Bibliográficos
Autores principales: Barton, Kelly L., Misuraca, Katherine, Cordero, Francisco, Dobrikova, Elena, Min, Hooney D., Gromeier, Matthias, Kirsch, David G., Becher, Oren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788718/
https://www.ncbi.nlm.nih.gov/pubmed/24098593
http://dx.doi.org/10.1371/journal.pone.0077639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788718/
https://www.ncbi.nlm.nih.gov/pubmed/24098593
http://dx.doi.org/10.1371/journal.pone.0077639

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