Structural Insights into Neutrophilic Migration Revealed by the Crystal Structure of the Chemokine Receptor CXCR2 in Complex with the First PDZ Domain of NHERF1

Neutrophil plays an essential role in host defense against infection, but uncontrolled neutrophilic infiltration can cause inflammation and severe epithelial damage. We recently showed that CXCR2 formed a signaling complex with NHERF1 and PLC-2, and that the formation of this complex was required fo...

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Detalles Bibliográficos
Autores principales: Lu, Guorong, Wu, Yanning, Jiang, Yuanyuan, Wang, Shuo, Hou, Yuning, Guan, Xiaoqing, Brunzelle, Joseph, Sirinupong, Nualpun, Sheng, Shijie, Li, Chunying, Yang, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788737/
https://www.ncbi.nlm.nih.gov/pubmed/24098448
http://dx.doi.org/10.1371/journal.pone.0076219

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