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Protein Disulfide Isomerase Interacts with Tau Protein and Inhibits Its Fibrillization

BACKGROUND: Tau protein is implicated in the pathogenesis of neurodegenerative disorders such as tauopathies including Alzheimer disease, and Tau fibrillization is thought to be related to neuronal toxicity. Physiological inhibitors of Tau fibrillization hold promise for developing new strategies fo...

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Detalles Bibliográficos
Autores principales: Xu, Li-Rong, Liu, Xiao-Ling, Chen, Jie, Liang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788760/
https://www.ncbi.nlm.nih.gov/pubmed/24098548
http://dx.doi.org/10.1371/journal.pone.0076657