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Protein Disulfide Isomerase Interacts with Tau Protein and Inhibits Its Fibrillization
BACKGROUND: Tau protein is implicated in the pathogenesis of neurodegenerative disorders such as tauopathies including Alzheimer disease, and Tau fibrillization is thought to be related to neuronal toxicity. Physiological inhibitors of Tau fibrillization hold promise for developing new strategies fo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788760/ https://www.ncbi.nlm.nih.gov/pubmed/24098548 http://dx.doi.org/10.1371/journal.pone.0076657 |