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A Phase II, Randomized, Double-Blind, Placebo Controlled, Dose-Response Trial of the Melatonin Effect on the Pain Threshold of Healthy Subjects
BACKGROUND: Previous studies have suggested that melatonin may produce antinociception through peripheral and central mechanisms. Based on the preliminary encouraging results of studies of the effects of melatonin on pain modulation, the important question has been raised of whether there is a dose...
Autores principales: | Stefani, Luciana Cadore, Muller, Suzana, Torres, Iraci L. S., Razzolini, Bruna, Rozisky, Joanna R., Fregni, Felipe, Markus, Regina, Caumo, Wolnei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788771/ https://www.ncbi.nlm.nih.gov/pubmed/25947930 http://dx.doi.org/10.1371/journal.pone.0074107 |
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