Cargando…

Antioxidant N-Acetylcysteine Attenuates Hepatocarcinogenesis by Inhibiting ROS/ER Stress in TLR2 Deficient Mouse

Hepatocellular carcinoma (HCC) remains one of the most deadly solid tumor malignancies worldwide. We recently find that the loss of toll-like receptor 2 (TLR2) activities promotes the diethylnitrosamine (DEN) induced hepatocellular carcinogenesis and tumor progression, which associates with an abund...

Descripción completa

Detalles Bibliográficos
Autores principales: Lin, Heng, Liu, Xiao-bo, Yu, Jiao-jiao, Hua, Fang, Hu, Zhuo-wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788783/
https://www.ncbi.nlm.nih.gov/pubmed/24098333
http://dx.doi.org/10.1371/journal.pone.0074130