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CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report

Brain metastasis is a significant cause of morbidity and mortality and a critical complication of non-central nervous system primary carcinoma. The present study describes the clinical case of a 46-year-old male with lung cancer and life-threatening brain metastases. The patient was diagnosed with l...

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Autores principales: YANG, GUIQING, WANG, YISHAN, WANG, YUANYUAN, LIN, SIXIANG, SUN, DONGNING
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788854/
https://www.ncbi.nlm.nih.gov/pubmed/24137362
http://dx.doi.org/10.3892/ol.2013.1383
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author YANG, GUIQING
WANG, YISHAN
WANG, YUANYUAN
LIN, SIXIANG
SUN, DONGNING
author_facet YANG, GUIQING
WANG, YISHAN
WANG, YUANYUAN
LIN, SIXIANG
SUN, DONGNING
author_sort YANG, GUIQING
collection PubMed
description Brain metastasis is a significant cause of morbidity and mortality and a critical complication of non-central nervous system primary carcinoma. The present study describes the clinical case of a 46-year-old male with lung cancer and life-threatening brain metastases. The patient was diagnosed with lung cancer with a clinical stage of T2N0M1 (stage IV). Six months after the initial diagnosis and administration of conformal radiotherapy combined with three cycles of chemotherapy, an enhanced computed tomography (CT) scan of the brain revealed abnormalities with double-dosing of intravenous contrast. The CT scan identified >24 lesions scattered in the whole brain. The patient was treated with three-fraction Cyberknife radiotherapy at 22 Gy, delivered to the brain metastases at the Center for Tumor Treatment of People’s Liberation Army 107th Hospital. Following CyberKnife therapy, a CT scan of the brain revealed that most of the tumors had disappeared with almost no residual traces. The stereotactic radiosurgery (SRS) conducted using CyberKnife, an image-guided frameless robotic technology for whole-body radiosurgery, had produced a marked response. The present case report demonstrates that CyberKnife therapy plays a significant role in the management of multiple meta-static brain tumors.
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spelling pubmed-37888542013-10-17 CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report YANG, GUIQING WANG, YISHAN WANG, YUANYUAN LIN, SIXIANG SUN, DONGNING Oncol Lett Articles Brain metastasis is a significant cause of morbidity and mortality and a critical complication of non-central nervous system primary carcinoma. The present study describes the clinical case of a 46-year-old male with lung cancer and life-threatening brain metastases. The patient was diagnosed with lung cancer with a clinical stage of T2N0M1 (stage IV). Six months after the initial diagnosis and administration of conformal radiotherapy combined with three cycles of chemotherapy, an enhanced computed tomography (CT) scan of the brain revealed abnormalities with double-dosing of intravenous contrast. The CT scan identified >24 lesions scattered in the whole brain. The patient was treated with three-fraction Cyberknife radiotherapy at 22 Gy, delivered to the brain metastases at the Center for Tumor Treatment of People’s Liberation Army 107th Hospital. Following CyberKnife therapy, a CT scan of the brain revealed that most of the tumors had disappeared with almost no residual traces. The stereotactic radiosurgery (SRS) conducted using CyberKnife, an image-guided frameless robotic technology for whole-body radiosurgery, had produced a marked response. The present case report demonstrates that CyberKnife therapy plays a significant role in the management of multiple meta-static brain tumors. D.A. Spandidos 2013-08 2013-06-07 /pmc/articles/PMC3788854/ /pubmed/24137362 http://dx.doi.org/10.3892/ol.2013.1383 Text en Copyright © 2013, Spandidos Publications http://creativecommons.org/licenses/by/3.0 This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Articles
YANG, GUIQING
WANG, YISHAN
WANG, YUANYUAN
LIN, SIXIANG
SUN, DONGNING
CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title_full CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title_fullStr CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title_full_unstemmed CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title_short CyberKnife therapy of 24 multiple brain metastases from lung cancer: A case report
title_sort cyberknife therapy of 24 multiple brain metastases from lung cancer: a case report
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788854/
https://www.ncbi.nlm.nih.gov/pubmed/24137362
http://dx.doi.org/10.3892/ol.2013.1383
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