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Progressive endothelin-1 gene activation initiates chronic/end stage renal disease following experimental ischemic-reperfusion injury

This study assessed whether endothelin-1 (ET1) helps mediate post-ischemic acute kidney injury (AKI) progression to chronic kidney disease (CKD). The impact(s) of potent ETA or ETB receptor-specific antagonists (Atrasentan and BQ-788, respectively) on disease progression were assessed 24 hours or 2...

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Detalles Bibliográficos
Autores principales:	Zager, Richard A., Johnson, Ali CM, Andress, Dennis, Becker, Kirsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788861/ https://www.ncbi.nlm.nih.gov/pubmed/23698233 http://dx.doi.org/10.1038/ki.2013.157

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