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Drug-primed reinstatement of cocaine seeking in mice: increased excitability of medium-sized spiny neurons in the nucleus accumbens
To examine the mechanisms of drug relapse, we first established a model for cocaine IVSA (intravenous self-administration) in mice, and subsequently examined electrophysiological alterations of MSNs (medium-sized spiny neurons) in the NAc (nucleus accumbens) before and after acute application of coc...
Autores principales: | Ma, Yao-Ying, Henley, Sandy M., Toll, Jeff, Jentsch, James D., Evans, Christopher J., Levine, Michael S., Cepeda, Carlos |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Neurochemistry
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789142/ https://www.ncbi.nlm.nih.gov/pubmed/24000958 http://dx.doi.org/10.1042/AN20130015 |
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