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Neuronal STAT3 activation is essential for CNTF- and inflammatory stimulation-induced CNS axon regeneration
CNS neurons, such as retinal ganglion cells (RGCs), do not normally regenerate injured axons, but instead undergo apoptotic cell death. Regenerative failure is due to inhibitory factors in the myelin and forming glial scar as well as due to an insufficient intrinsic capability of mature neurons to r...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789169/ https://www.ncbi.nlm.nih.gov/pubmed/24052073 http://dx.doi.org/10.1038/cddis.2013.310 |