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A new platinum(II) compound anticancer drug candidate with selective cytotoxicity for breast cancer cells
[Pt(O,O′-acac)(γ-acac)(DMS)] (PtAcD) is able to induce apoptosis in various human cancer cells, including the cisplatin-resistant human breast carcinoma MCF-7 cells. Here, to confirm that PtAcD has the potentiality for therapeutic intervention, we studied its effects in primary cultured epithelial b...
Autores principales: | Muscella, A, Vetrugno, C, Fanizzi, F P, Manca, C, De Pascali, S A, Marsigliante, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789173/ https://www.ncbi.nlm.nih.gov/pubmed/24030148 http://dx.doi.org/10.1038/cddis.2013.315 |
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