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p38 MAPK signaling acts upstream of LIF-dependent neuroprotection during photoreceptor degeneration

In many blinding diseases of the retina, loss of function and thus severe visual impairment results from apoptotic cell death of damaged photoreceptors. In an attempt to survive, injured photoreceptors generate survival signals to induce intercellular protective mechanisms that eventually may rescue...

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Detalles Bibliográficos
Autores principales: Agca, C, Gubler, A, Traber, G, Beck, C, Imsand, C, Ail, D, Caprara, C, Grimm, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789181/
https://www.ncbi.nlm.nih.gov/pubmed/24008729
http://dx.doi.org/10.1038/cddis.2013.323