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Long-term survival in multiple myeloma is associated with a distinct immunological profile, which includes proliferative cytotoxic T-cell clones and a favourable Treg/Th17 balance
Despite improved outcomes in multiple myeloma (MM), a cure remains elusive. However, even before the current therapeutic era, 5% of patients survived >10 years and we propose that immune factors contribute to this longer survival. We identified patients attending our clinic, who had survived >...
Autores principales: | Bryant, C, Suen, H, Brown, R, Yang, S, Favaloro, J, Aklilu, E, Gibson, J, Ho, P J, Iland, H, Fromm, P, Woodland, N, Nassif, N, Hart, D, Joshua, D E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789202/ https://www.ncbi.nlm.nih.gov/pubmed/24036947 http://dx.doi.org/10.1038/bcj.2013.34 |
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