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U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis

MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of qPCR demands appropriate normalization to correct for nonbiological variation. Pres...

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Detalles Bibliográficos
Autores principales: Benz, Fabian, Roderburg, Christoph, Vargas Cardenas, David, Vucur, Mihael, Gautheron, Jérémie, Koch, Alexander, Zimmermann, Henning, Janssen, Jörn, Nieuwenhuijsen, Lukas, Luedde, Mark, Frey, Norbert, Tacke, Frank, Trautwein, Christian, Luedde, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789266/
https://www.ncbi.nlm.nih.gov/pubmed/24052167
http://dx.doi.org/10.1038/emm.2013.81