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U6 is unsuitable for normalization of serum miRNA levels in patients with sepsis or liver fibrosis
MicroRNA (miRNA) levels in serum have recently emerged as potential novel biomarkers for various diseases. miRNAs are routinely measured by standard quantitative real-time PCR (qPCR); however, the high sensitivity of qPCR demands appropriate normalization to correct for nonbiological variation. Pres...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789266/ https://www.ncbi.nlm.nih.gov/pubmed/24052167 http://dx.doi.org/10.1038/emm.2013.81 |