Oncogenic Brain Metazoan Parasite Infection

Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis,...

Descripción completa

Detalles Bibliográficos
Autores principales: Spurgeon, Angela N., Cress, Marshall C., Gabor, Oroszi, Ding, Qing-Qing, Tanaka, Tomoko, Miller, Douglas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789294/
https://www.ncbi.nlm.nih.gov/pubmed/24151568
http://dx.doi.org/10.1155/2013/263718
_version_ 1782286427935997952
author Spurgeon, Angela N.
Cress, Marshall C.
Gabor, Oroszi
Ding, Qing-Qing
Tanaka, Tomoko
Miller, Douglas C.
author_facet Spurgeon, Angela N.
Cress, Marshall C.
Gabor, Oroszi
Ding, Qing-Qing
Tanaka, Tomoko
Miller, Douglas C.
author_sort Spurgeon, Angela N.
collection PubMed
description Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship.
format Online
Article
Text
id pubmed-3789294
institution National Center for Biotechnology Information
language English
publishDate 2013
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-37892942013-10-22 Oncogenic Brain Metazoan Parasite Infection Spurgeon, Angela N. Cress, Marshall C. Gabor, Oroszi Ding, Qing-Qing Tanaka, Tomoko Miller, Douglas C. Case Rep Neurol Med Case Report Multiple observations suggest that certain parasitic infections can be oncogenic. Among these, neurocysticercosis is associated with increased risk for gliomas and hematologic malignancies. We report the case of a 71-year-old woman with colocalization of a metazoan parasite, possibly cysticercosis, and a WHO grade IV neuroepithelial tumor with exclusively neuronal differentiation by immunohistochemical stains (immunopositive for synaptophysin, neurofilament protein, and Neu-N and not for GFAP, vimentin, or S100). The colocalization and temporal relationship of these two entities suggest a causal relationship. Hindawi Publishing Corporation 2013 2013-09-18 /pmc/articles/PMC3789294/ /pubmed/24151568 http://dx.doi.org/10.1155/2013/263718 Text en Copyright © 2013 Angela N. Spurgeon et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Spurgeon, Angela N.
Cress, Marshall C.
Gabor, Oroszi
Ding, Qing-Qing
Tanaka, Tomoko
Miller, Douglas C.
Oncogenic Brain Metazoan Parasite Infection
title Oncogenic Brain Metazoan Parasite Infection
title_full Oncogenic Brain Metazoan Parasite Infection
title_fullStr Oncogenic Brain Metazoan Parasite Infection
title_full_unstemmed Oncogenic Brain Metazoan Parasite Infection
title_short Oncogenic Brain Metazoan Parasite Infection
title_sort oncogenic brain metazoan parasite infection
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789294/
https://www.ncbi.nlm.nih.gov/pubmed/24151568
http://dx.doi.org/10.1155/2013/263718
work_keys_str_mv AT spurgeonangelan oncogenicbrainmetazoanparasiteinfection
AT cressmarshallc oncogenicbrainmetazoanparasiteinfection
AT gabororoszi oncogenicbrainmetazoanparasiteinfection
AT dingqingqing oncogenicbrainmetazoanparasiteinfection
AT tanakatomoko oncogenicbrainmetazoanparasiteinfection
AT millerdouglasc oncogenicbrainmetazoanparasiteinfection

Ejemplares similares