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Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma
Small cell carcinoma (SmCC) most commonly occurs in the lung and rarely arises from the head and neck region. Further, composite SmCC is extremely rare. Therefore, no postoperative treatment strategy has been established. We report a 59-year-old male patient referred to our outpatient clinic for fur...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789361/ https://www.ncbi.nlm.nih.gov/pubmed/24159397 http://dx.doi.org/10.1155/2013/806284 |
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author | Ebisumoto, Koji Sakai, Akihiro Okami, Kenji Sugimoto, Ryousuke Saito, Kosuke Iida, Masahiro |
author_facet | Ebisumoto, Koji Sakai, Akihiro Okami, Kenji Sugimoto, Ryousuke Saito, Kosuke Iida, Masahiro |
author_sort | Ebisumoto, Koji |
collection | PubMed |
description | Small cell carcinoma (SmCC) most commonly occurs in the lung and rarely arises from the head and neck region. Further, composite SmCC is extremely rare. Therefore, no postoperative treatment strategy has been established. We report a 59-year-old male patient referred to our outpatient clinic for further examination and treatment of a laryngeal tumor. Biopsy from the tumor revealed squamous cell carcinoma (SCC). The preoperative diagnosis was supraglottic SCC (T3N2bM0), and total laryngectomy and bilateral neck dissection were performed. Pathological examination revealed 2 individual cancer components: SmCC and SCC. Postoperative chemoradiotherapy (2 courses of cisplatin (CDDP) and etoposide (VP-16)) was indicated. Following the postoperative chemoradiotherapy, 2 courses of adjuvant chemotherapy were administered. The patient is currently alive with no evidence of disease at 36 months following the completion of therapy. Postoperative chemoradiotherapy and adjuvant chemotherapy are optimal treatment strategies for laryngeal composite SmCC. |
format | Online Article Text |
id | pubmed-3789361 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Hindawi Publishing Corporation |
record_format | MEDLINE/PubMed |
spelling | pubmed-37893612013-10-24 Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma Ebisumoto, Koji Sakai, Akihiro Okami, Kenji Sugimoto, Ryousuke Saito, Kosuke Iida, Masahiro Case Rep Otolaryngol Case Report Small cell carcinoma (SmCC) most commonly occurs in the lung and rarely arises from the head and neck region. Further, composite SmCC is extremely rare. Therefore, no postoperative treatment strategy has been established. We report a 59-year-old male patient referred to our outpatient clinic for further examination and treatment of a laryngeal tumor. Biopsy from the tumor revealed squamous cell carcinoma (SCC). The preoperative diagnosis was supraglottic SCC (T3N2bM0), and total laryngectomy and bilateral neck dissection were performed. Pathological examination revealed 2 individual cancer components: SmCC and SCC. Postoperative chemoradiotherapy (2 courses of cisplatin (CDDP) and etoposide (VP-16)) was indicated. Following the postoperative chemoradiotherapy, 2 courses of adjuvant chemotherapy were administered. The patient is currently alive with no evidence of disease at 36 months following the completion of therapy. Postoperative chemoradiotherapy and adjuvant chemotherapy are optimal treatment strategies for laryngeal composite SmCC. Hindawi Publishing Corporation 2013 2013-09-15 /pmc/articles/PMC3789361/ /pubmed/24159397 http://dx.doi.org/10.1155/2013/806284 Text en Copyright © 2013 Koji Ebisumoto et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Ebisumoto, Koji Sakai, Akihiro Okami, Kenji Sugimoto, Ryousuke Saito, Kosuke Iida, Masahiro Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title | Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title_full | Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title_fullStr | Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title_full_unstemmed | Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title_short | Optimal Postoperative Treatment for Composite Laryngeal Small Cell Carcinoma |
title_sort | optimal postoperative treatment for composite laryngeal small cell carcinoma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789361/ https://www.ncbi.nlm.nih.gov/pubmed/24159397 http://dx.doi.org/10.1155/2013/806284 |
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