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Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes
Karyopherin proteins mediate nucleocytoplasmic trafficking and are critical for protein and RNA subcellular localization. Recent studies suggest KPNA2 expression is induced in tumor cells and is strongly associated with prognosis, although the precise roles and mechanisms of KPNA2 overexpression in...
Autores principales: | Umegaki-Arao, Noriko, Tamai, Katsuto, Nimura, Keisuke, Serada, Satoshi, Naka, Tetsuji, Nakano, Hajime, Katayama, Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789663/ https://www.ncbi.nlm.nih.gov/pubmed/24098495 http://dx.doi.org/10.1371/journal.pone.0076416 |
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