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Karyopherin Alpha2 Is Essential for rRNA Transcription and Protein Synthesis in Proliferative Keratinocytes

Karyopherin proteins mediate nucleocytoplasmic trafficking and are critical for protein and RNA subcellular localization. Recent studies suggest KPNA2 expression is induced in tumor cells and is strongly associated with prognosis, although the precise roles and mechanisms of KPNA2 overexpression in...

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Detalles Bibliográficos
Autores principales: Umegaki-Arao, Noriko, Tamai, Katsuto, Nimura, Keisuke, Serada, Satoshi, Naka, Tetsuji, Nakano, Hajime, Katayama, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789663/
https://www.ncbi.nlm.nih.gov/pubmed/24098495
http://dx.doi.org/10.1371/journal.pone.0076416

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