Cytokine Profile in a Cohort of Healthy Blood Donors Carrying Polymorphisms in Genes Encoding the NLRP3 Inflammasome

BACKGROUND: The NLRP3 inflammasome has been recognized as one of the key components of the innate immunity by sensing a diversity of insults. Inflammasome activation results in the maturation of the pro-inflammatory cytokines interleukin (IL)-1β and IL-18. Increased production of IL-1β is found in p...

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Detalles Bibliográficos
Autores principales: Sahdo, Berolla, Fransén, Karin, Asfaw Idosa, Berhane, Eriksson, Per, Söderquist, Bo, Kelly, Anne, Särndahl, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789710/
https://www.ncbi.nlm.nih.gov/pubmed/24098386
http://dx.doi.org/10.1371/journal.pone.0075457

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