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Stat3 Inhibition Attenuates Mechanical Allodynia through Transcriptional Regulation of Chemokine Expression in Spinal Astrocytes

BACKGROUND: Signal transducer and activator of transcription 3 (Stat3) is known to induce cell proliferation and inflammation by regulating gene transcription. Recent studies showed that Stat3 modulates nociceptive transmission by reducing spinal astrocyte proliferation. However, it is unclear wheth...

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Detalles Bibliográficos
Autores principales:	Liu, Xiaodong, Tian, Yuanyuan, Lu, Na, Gin, Tony, Cheng, Christopher H. K., Chan, Matthew T. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789727/ https://www.ncbi.nlm.nih.gov/pubmed/24098399 http://dx.doi.org/10.1371/journal.pone.0075804

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