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The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense
Trypanosoma brucei gambiense causes 97% of all cases of African sleeping sickness, a fatal disease of sub-Saharan Africa. Most species of trypanosome, such as T. b. brucei, are unable to infect humans due to the trypanolytic serum protein apolipoprotein-L1 (APOL1) delivered via two trypanosome lytic...
Autores principales: | Capewell, Paul, Clucas, Caroline, DeJesus, Eric, Kieft, Rudo, Hajduk, Stephen, Veitch, Nicola, Steketee, Pieter C., Cooper, Anneli, Weir, William, MacLeod, Annette |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789759/ https://www.ncbi.nlm.nih.gov/pubmed/24098129 http://dx.doi.org/10.1371/journal.ppat.1003686 |
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