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Ligand Clouds around Protein Clouds: A Scenario of Ligand Binding with Intrinsically Disordered Proteins
Intrinsically disordered proteins (IDPs) were found to be widely associated with human diseases and may serve as potential drug design targets. However, drug design targeting IDPs is still in the very early stages. Progress in drug design is usually achieved using experimental screening; however, th...
Autores principales: | Jin, Fan, Yu, Chen, Lai, Luhua, Liu, Zhirong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3789766/ https://www.ncbi.nlm.nih.gov/pubmed/24098099 http://dx.doi.org/10.1371/journal.pcbi.1003249 |
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